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This section is a compilation from various sources about the drugs you can take to greatly reduce withdrawal symptoms.

The exact timetable for the first few days of opiate withdrawal will depend on which opiate you are coming off of.  A shorter acting opiate (such as dilaudid) will accelerate the timing a bit.  On the other hand, methadone and buprenorphine (suboxone) are in a class by themselves because they are so long acting. Methadone is particularly difficult to detox from because it is fat soluble and has to be slowly released by your fat as part of the detox process.

Not allowing enough time for withdrawal before resuming “life” and the responsibilities that go with it is probably the number one reason for relapsing.   Assuming this is not your first time through withdrawal, you know how long it might take. Keep in mind that it gets harder with every withdrawal.  However, by working the suggestions below, you might be surprised how much easier it can be.

The following is a list of symptoms you might have during the first few days and what you can do to manage them.

Opiate Cravings: Perhaps one of the most distressing “symptoms” is the relentless craving to get high again.  Usually, you are told that you need to tough this out with will power.

However, there is a better way.  There are two drugs I know of that will heal you of your craving.

1.  Noopept.  This is a “smart drug” that seems to rewire the brain and heal the craving for opiates.  It is available on eBay.

2. Ketamine.  Pharmaceutical companies are currently in a mad rush to create a new patented version of this veterinary drug. This is because it is now recognized as a powerful antidepressant.  However, for some reason, it also seems to heal the brain of opiate cravings.  Ketamine is a pretty rare “street” drug to find, but there is an alternative.

Although Procaine is not nearly as effective as Ketamine, it will work – just more slowly. It is available as a supplement as part of formulations such as Vitacel 7 Plus.

Spacey feeling/Unable to Concentrate:  Ride it out with an inspiring book (if you can hyper focus by reading) or a selection of inspiring, funny or positive movies.  Stimulants such as dexadrine, methalphenidate (Ritalin), coffee, guarana, ginsing or Rhodiola help.  It is difficult to get a potent enough extract of the last two to be useful at this phase.

For that burning sensation in your insides, gabapentin works pretty well.

Fatigue or muscle weakness:  This is actually a continuation of the spacy feeling from the first day.  So, dexadrine, methalphenidate (Ritalin), coffee,  guarana, ginsing or Rhodiola all help.  But make sure that you don’t take so much that they mess with your sleep!  In addition, a potent B vitamin complex helps.  Unfortunately, gabapentin can make fatigue somewhat worse, but its ability to help with sleep more than offsets this difficulty.

L-Tyrosine can also help fight fatigue.  As with the stimulants mentioned above , the trick is getting the dosage right.   That dosage is likely between 2000 mg and 4000 mg.

Twitchy feeling or RLS:  having enough potassium and magnesium helps a lot.   You need a lot of both of these minerals every day anyway, so it is easy to become deficient.  You can get supplements containing just these two minerals. The best thing is to work on these deficiencies ahead of time.  However, bananas or avocados have a lot of potassium in case you can’t find a potassium supplement.  It is almost impossible to get enough magnesium anymore because almost all soils that food are grown in have been depleted of magnesium.  Slomag (available at Walgreens)  or its cheaper knockoff, MAG64 (available on the amazon.com and ebay.com) work well if you take 6 tablets a day.  But again, start at least a week before you plan to go through opiate withdrawal for best results.

High quality ginseng also seems to help with RLS.

Diarrhea: If I had one medication to take with my to a desert island to stave off a impending withdrawal, it would be Imodium, generic name Loperamide Hydrochloride.   It works wonders for all aspects of withdrawal except for the fatigue.  This is because Imodium IS actually an opiate – it just does not get into the brain, so it does not feel like an opiate.  However, your body will be spared the withdrawal, which turns out is  actually 90% of the battle. The trick is knowing how much to take.  If you do it right, you will feel “normal” with hardly any withdrawal symptoms.  You might only need an attack dose of 6 mg of Imodium (3 tablets) if you are coming off 15mg/day of Oxycontin.  Follow up with  4 mg every 12 hours.  If the withdrawal symptoms come back, take another 4 mg.

Start taking the Imodium when the first serious signs of withdrawal start to kick in. You can scale the dosage for different opiates and different daily amounts.  Do the math over at the opiate comparison chart. I’ve heard of people taking 40 mg Imodium for a more serious opiate dependence.  Like I said, you’ll know you have the amount of Imodium right because you’ll feel normal, if perhaps a bit weak.  It only takes about half an our for the Imodium to kick in on an empty stomach, and if you run low (relative to your need) the withdrawal symptoms will come back with a vengeance.  Just take more of your calcuated dose.  Imodium has a rather long half life of about 12 hours, so keep that in mind when deciding when to take more.

Advantage: less cravings, less anxiety, less depression.
Disadvantage: more spacey feeling, possible constipation.

You may still experience constipation while taking Imodium, so keep taking the stool softner (Docusate Sodium) until you can taper down from both after the first 4 days.

Another thing to consider – It is little known that opiates raise body temperature.  What happens without this support is that the body temperature drops below the optimum range without this support.  This is a temporary hypothyroidism. Among other things, this triggers painful diarrhea.  Fortunately, there is a fairly easy way to raise body temperature by using thyroid hormones.  Synthroid is very common medication, especially as you get older.  Tablets usually come in one grain sizes.   Somewhere between 2 and 8 grains, taken throughout the day, raise the body temperature enough to compensate for the temporary hypothyroidism.   There is also a supplement made my Natural Source called “Raw Thyroid.”  However it is not very strong and it appears that it takes about 4 capsules to equal one grain.  Don’t expect to find it in your health food store.  You need to order it from http://www.iherb.com/Natural-Sources-Raw-Thyroid-90-Capsules/6016?at=0

 Insomnia: Anything drug that raises GABA neurotransmitter levels at night. Examples are Valium, Xanax, benzodiazepine like sleeping pills. On the herbal side, valerian works well only if you have not recently used any of the drugs mentioned in the previous sentence.  Another option is gabapentin if you have not used it in the past year.  Gabapentin works really well the first few days you take it which happens to match the fact that you need something strong the first few days of opiate withdrawal. If I had a second drug to take with me to a desert island to stave off withdrawal, it would be gabapentin.

A streetdrug that works well is GHB.  However, it is easy to overdose on it. Be careful.

A safer alternative is Phenibut, which is available on eBay.  However, it is possible to build up a tolerance to Phenibut in a matter of days.

Chills and Hot Flashes: Clonidine.  This helps lower your blood pressure as well. This is a heavy duty drug.  I’ve not used it so do your own research.  A over the counter choice that works well is Imodium, once again.

Pain:  Over the counter pain relievers are the obvious choice, but what if that is not enough?  Supplement pain relief formulations such as Natural Tumericforce can be stacked on top of the over the over-the-counter products because of their low toxicity.  But, what if that is still not enough?  This is where you can quickly slip into dangerous territory because there is a herb available as “incense” that works very much like the opiates that you are trying to avoid, namely Kratom.  Google it.  Fair warning:  you may end up having to detox from Kratom

Also gabapentin helps with pain as well.  This is one of the common “off label” uses for this drug.

 

Fourth Day and After:

Because low level pains are likely to be felt more, depression ( or feeling blue ) is a danger.  Note that you don’t have to consciously be feeling pain for this phenomena or process to take effect.  Also, you will continue to have some difficulty with sleep.  These effects will gradually taper off.  This tapering time will be longer with if you are coming down from a high dosage, or from a long use period or if this withdrawal was preceded by lot of previous withdrawals. As you can see, because of the various factors, its hard to predict how quickly this tail will taper down.

It is important to treat the tail end of withdrawal because a relapse is much more likely if a proper treatment is not applied.  Various natural and pharmaceutical anti-depresents seem to work.  Gabapentin works particularly well because it as the effect of raising the GABA levels.  This decreases anxiety and makes sleep easier. For this reason, take the gabapentin in the evening.   Remember that it works really well for the first few days, and then the effect starts to wear off.  This closely matches the need during withdrawal.

SSRIs (such as prozac) also work, but they kick in slowly, they don’t match the need.  SAMe, andSt.Johns Wort also help and do not require a doctor visit.  You can get them at a good health food store as a supplement.

See also http://opiatewithdrawaltips.com/the-long-grind/ and http://opiatewithdrawaltips.com/paws/

9 Responses to Day 1 – 4

  • lorisa says:

    Appreciate your article. Interesting about immodium. Thought it was just for the stomach issues, didn’t realize it would help other things as well. Just wanting you to know you notes helped someone!

  • Linda says:

    Hi there. Why does gabapentin only work for withdrawals if u haven’t taken it in the past year? Ur quick response would be greatly appreciated! Thank u!

  • edward says:

    Awesome info esp about the imodium I so wish I knew that last time I kicked thx for the info.

  • The White Rabbit says:

    Two very dear friends of mine died in their sleep and the toxicology reports indicated the only things in their systems were Imodium & kratom.

    • crimnt says:

      Not sure why my phone is doing all caps. Anyway, thats bs ‘the white rabbit’. Unless they took over 150mg or maybe over 200mg i can see where they could of died.

  • sarah says:

    I can’t imagine ketamine being safe as it is a powerful sedative which frequently causes adults to hallucinate. I would avoid drugs such as this if you’re ultimate goal is to come out alive .

  • Catryna says:

    SORRY ABOUT THE ALL CAPS, JUST GOT A CHROMEBOOK AND IT DOESN’T HAVE A REGULAR CAPS LOCK OR UNLOCK KEY….
    i’VE BEEN ON METHADONE FOR OVER 10 YEARS AND HAVE TRIED A COUPLE OF TIME COLD TURKEY TO QUIT. i WAS ON 105MG, YES 105 MG! i QUIT WITH THE HELP OF 5HTP AND A B-COMPLEX. i STARTED TAKING BOTH OF THEM 1 MONTH PRIOR TO STOPPING AND IT’S BEEN 2 WEEKS NOW AND i GOTTA SAY, SINCE DAY ONE IT WAS NEVER AS BAD AS IT WAS LAST TIME. i KEPT WAITING TO GET WORSE BEFORE i GOT BETTER AND IT NEVER HAPPENED. i TOOK 200MG OF 5HTP er TWICE A DAY OR EVERY 12 HOURS FOR THE 1ST WEEK AND THEN BACK TO 100MG TWICE A DAY FOR THIS LAST WEEK AND i FEEL GREAT!
    OBVIOUSLY CHECK WITH YOUR DOC BUT IF YOU CAN, TRY 5HTP, IT SAVED MY LIFE!!

  • crimnt says:

    Immodium (loperamide) does in fact cross the blood brain barrier. I take 40-50mg of the 2mg pills and it makes my withdrawals way more managable. Begginers should take 25-30mg until you asses yohr tolerance. Liquid immodium gets in your blood stream faster. You can get high off it so make sure you eventually taper off immodium cause it can cause withdrawals! Want more info on how to use immodium for opiate detox emai me ancolon24 at gmail dot com

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